How do I setup my connection string so that communication with the SQL server is encrypted?

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The connection string below is an example that specifies the use of encryption. Essentially you are using the connection string from the SQL section of your web.config and adding encrypt=true to the end. Setting the encrypt property to true will cause the transmission of data to and from the SQL server to be encrypted. 

     <add name="MyConnection" connectionString="Data;Initial Catalog=DB_XXX_db1;User ID=DB1_user;Password=*****; encrypt=true;TrustServerCertificate=True" providerName="System.Data.SqlClient"/>